HuagongsheHuagongshe Chemistry Print Report · For research reference only
11-chlorocarbonyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one → HCID 19846028, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 11-chlorocarbonyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | HCID 11043962 | — |
| Reactant | HCID 14210012 | HCID 14210012 | — |
| Product | HCID 19846028 | HCID 19846028 | 52% |
Reaction Steps
Prepared analogously to Example 2 from 11-(chlorocarbonyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 2-[2-[2-(dimethylamino)ethyl]-piperidin-1-yl]-N-methyl-ethanamine in a yield of 52% of theory. Colourless crystals, m.p. 114°-116° C. (after recrystallisation from diisopropylether and acetonitrile and decoction with water).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04873236 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-7f2f68b9358a4d338bfdb1d4acb89d1f |
| Source note | uspto-grants-1989_10 |