HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-chlorocarbonyl-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one → HCID 54560141, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-chlorocarbonyl-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one | HCID 14209980 | — |
| Reactant | HCID 19845999 | HCID 19845999 | — |
| Solvent | tert-Butyl methyl ether | HCID 15413 | — |
| Product | HCID 54560141 | HCID 54560141 | 17% |
Reaction Steps
Prepared analogously to Example 1 from 4-(chlorocarbonyl)-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one and 2-[4-[3-(dimethylamino)propyl]-piperidin-l-yl]ethanamine in a yield of 17% of theory. Colourless crystals, m.p. >300° C. (t-butylmethyl ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04873236 |
| Source dataset | uspto-grants-1989_10 |
| ORD ID | ord-d824994e9a004847b5899bf609f977dc |
| Source note | uspto-grants-1989_10 |