Hydrochloric Acid → HCID 15613923, compound

Participants

Reaction Steps

Following a procedure similar to that described in Example 1, but using 1.52 g of ethyl 2-chloro-3-[4-(2,5,7-trimethylchroman-2-ylmethoxy)phenyl]propionate (prepared as described in Preparation 27), 0.83 g of thiourea, 5 ml of sulfolane, 15 ml of ethylene glycol monomethyl ether and 4 ml of 3N aqueous hydrochloric acid, 1.18 g of the title compound were obtained as a pale yellow powder, softening at 85°-108° C.

Provenance & Evidence