Hydrochloric Acid → HCID 15671166, compound

Participants

Reaction Steps

Following a procedure similar to that described in Example 1, but using 1.5 g of ethyl 2-chloro-3-[4-(2,5,7-trimethyl-4-oxochroman-2-ylmethoxy)phenyl]propionate (prepared as described in Preparation 29), 0.4 g of thiourea, 1.5 ml of sulfolane, 10 ml of ethylene glycol monomethyl ether and 5 ml of 2N aqueous hydrochloric acid, 1.13 g of the title compound were obtained as a pale yellow powder.

Provenance & Evidence