Hydrochloric Acid → HCID 15613925, compound

Participants

Reaction Steps

Following a procedure similar to that described in Example 1, but using 361 mg of ethyl 2-chloro-3-[4-(2,5,6,7,8-pentamethylchroman-2-ylmethoxy)phenyl]propionate (prepared as described in Preparation 33), 309 mg of thiourea, 3 ml of sulfolane, 10 ml of ethylene glycol monomethyl ether and 5 ml of 3N aqueous hydrochloric acid, 290 mg of the title compound were obtained as a white powder, softening at 62°-64° C.

Provenance & Evidence