Hydrochloric Acid → HCID 15671150, compound

Participants

Reaction Steps

A procedure similar to that described in Preparation 5 was repeated, except that 1.8 g of 2-(4-aminophenoxymethyl)-2,5,7-trimethyl-4-oxochroman (prepared as described in Preparation 28), 2 ml of concentrated aqueous hydrochloric acid, 520 mg of sodium nitrite, 6 ml of ethyl acrylate, 83 mg of cuprous oxide, 20 ml of acetone and 1 ml of water were reacted, to afford 1.52 g of the title compound as a pale yellow oil.

Provenance & Evidence