Hydrochloric Acid → HCID 15671162, compound

Participants

Reaction Steps

A procedure similar to that described in Preparation 5 was repeated, except that 1.44 g of 6-acetoxy-2-(4-aminophenoxymethyl)-7-chloro-2-methyl-4-oxochroman (prepared as described in Preparation 36), 1.8 ml of concentrated aqueous hydrochloric acid, 330 mg of sodium nitrite, 18 ml of acetone, 3.7 ml of ethyl acrylate, 330 mg of cuprous oxide and 3 ml of water were reacted, to afford 600 mg of the title compound as a pale yellow oil.

Provenance & Evidence