Sodium borohydride → HCID 15671130, compound

HRID 2351528Notes

Reaction equation

HRID 2351528 reaction equation
[C:1]([O:4][C:5]1[C:14]([CH3:15])=[C:13]2[C:8]([C:9](=[O:28])[CH2:10][C:11]([CH3:27])([CH2:16][O:17][C:18]3[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=3)[O:12]2)=[CH:7][CH:6]=1)(=[O:3])[CH3:2].[BH4-].[Na+]>CO>[C:1]([O:4][C:5]1[C:14]([CH3:15])=[C:13]2[C:8]([CH:9]([OH:28])[CH2:10][C:11]([CH3:27])([CH2:16][O:17][C:18]3[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=3)[O:12]2)=[CH:7][CH:6]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 15671128HCID 15671128, compound

Product 1

HCID 15671130HCID 15671130, compoundYield 55.1%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A procedure similar to that described in Preparation 2 was repeated, except that 5 g of 7-acetoxy-2,8-dimethyl-2-(4-nitrophenoxymethyl)-4-oxochroman (prepared as described in Preparation 17), 980 mg of sodium borohydride and 20 ml of methanol were reacted, to afford 2.77 g of the title compound as a pale yellow oil.

Workup

  1. customA procedure similar to that described in Preparation 2
  2. customwere reacted

Sources & evidence

ORD record
ord-613ee3793f604ab18001664748dcf9b4
Source dataset
uspto-grants-1989_10
Patent number
US04873255

Reaction notes

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