HCID 15671135, compound → HCID 15671139, compound

HRID 2351529Notes

Reaction equation

HRID 2351529 reaction equation
[C:1]([O:4][C:5]1[C:14]([CH3:15])=[C:13]2[C:8]([CH:9]=[CH:10][C:11]([CH3:27])([CH2:16][O:17][C:18]3[CH:23]=[CH:22][C:21]([N+:24]([O-])=O)=[CH:20][CH:19]=3)[O:12]2)=[CH:7][CH:6]=1)(=[O:3])[CH3:2]>[Pd].CO>[C:1]([O:4][C:5]1[C:14]([CH3:15])=[C:13]2[C:8]([CH2:9][CH2:10][C:11]([CH2:16][O:17][C:18]3[CH:19]=[CH:20][C:21]([NH2:24])=[CH:22][CH:23]=3)([CH3:27])[O:12]2)=[CH:7][CH:6]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 1

HCID 15671135HCID 15671135, compound

Product 1

HCID 15671139HCID 15671139, compoundYield 91.3%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Following a procedure similar to that described in Preparation 4, 1.6 g of 7-acetoxy-2,8-dimethyl-2-(4-nitrophenoxymethyl)-2H-chromene (prepared as described in Preparation 39) was hydrogenated, using 0.2 g of 10% w/w palladium-on-carbon and 15 ml of methanol, to afford 1.35 g of the title compound as a pale brown oil.

Sources & evidence

ORD record
ord-7f1a5a01788b4011a338e70e79e1b6d7
Source dataset
uspto-grants-1989_10
Patent number
US04873255

Reaction notes

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