Hydrochloric Acid → HCID 15671143, compound

Participants

Reaction Steps

A procedure similar to that described in Preparation 5 was repeated, except that 1.3 g of 7-acetoxy-2-(4-aminophenoxymethyl)-2,8-dimethylchroman (prepared as described in Preparation 40), 340 mg of sodium nitrite, 1.3 ml of concentrated aqueous hydrochloric acid, 4 ml of ethyl acrylate, 60 mg of cuprous oxide, 10 ml of acetone and 0.5 ml of water were reacted, to afford 1.0 g of the title compound as a pale yellow oil.

Provenance & Evidence