HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2351581Generated: October 26, 2026
Chloroform → 1-Chloro-2-methylpropyl propanoate
https://huagongshe.com/reaction/2351581
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Isobutyraldehyde | HCID 6561 | — |
| Reactant | Propionyl chloride | HCID 62324 | — |
| Catalyst | Zincchloride | HCID 3007855 | — |
| Product | 1-Chloro-2-methylpropyl propanoate | HCID 12661010 | — |
Reaction Steps
To a vigorously stirred, ice-cooled solution of propionyl chloride (1407 g, 14.8 moles) in 3A sieve-dried chloroform (3000 ml) was added zinc chloride (7.4 g) followed by the dropwise addition (exotherm) of isobutyraldehyde (1132 g, 14.8 moles) at such a rate that the temperature was maintained at 25° C. (three hours).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04873356 |
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| Source dataset | uspto-grants-1989_10 |
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| ORD ID | ord-05aba4964ae942478be0a2251e9b598d |
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| Source note | uspto-grants-1989_10 |
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