反应详情

To a solution of bromide 40 (0.29 g, 1.30 mmol) in dry acetone (10 mL) was added NaI (0.26 g, 1.70 mmol). The reaction mixture was stirred for 5 min, filtered, and poured into Et2O (50 mL) and water (20 mL). The ether layer was separated, washed with three 20-mL portions of water, dried over Na2SO4, and concentrated by rotary evaporation to yield the iodide 34 (0.35 g, 100%). The iodide was used immediately without further purification. If the reaction mixture was stirred for longer than 5 min, isomerization of the cis- to the transallyl iodide began to take place.

1. filtrationfiltered
2. additionpoured into Et2O (50 mL) and water (20 mL)
3. customThe ether layer was separated
4. washwashed with three 20-mL portions of water
5. dry with materialdried over Na2SO4
6. concentrationconcentrated by rotary evaporation