反应详情

温度

50 °C

The reaction mixture was cooled to 50° C. and the residual pressure was released, and 70 ml of benzene was added into the autoclave to dissolve the oil layer. The catalyst was removed by filtration, and the filtrate was allowed to stand still to cause phase separation to give a benzene layer. Then, the benzene layer was washed with 100 ml of water three times, and benzene was removed by distillation under reduced pressure to give an oily product. From the results of the analysis of oil product by gas chromatography according to the internal standard method, it was found that the oily product comprised 98.6% of 3-phenoxybenzyl 2-(4-ethoxyphenyl)-2-methylpropyl ether and 0.4% of unreacted starting 3-phenoxybenzyl 2-(3-bromo-4-ethoxyphenyl)-2-methylpropyl ether, and that the content of each of 3-phenoxytoluene and 4-ethoxyneophyl alcohol formed by cleaving of the ether linkage was lower than 0.3%. The amount of the obtained oily product was 23.8 g and the yield was 94.4%.

1. dissolutionto dissolve the oil layer
2. customThe catalyst was removed by filtration
3. customphase separation
4. customto give a benzene layer
5. washThen, the benzene layer was washed with 100 ml of water three times, and benzene
6. customwas removed by distillation under reduced pressure
7. customto give an oily product
8. customFrom the results of the analysis of oil product by gas chromatography