Sodium Hydroxide → HCID 13773368, compound

Participants

Reaction Steps

15% Aqueous sodium hydroxide (3 ml) is added to a stirred solution of ethyl-2-(4-chlorophenyl)-3(trifluoromethyl)-but-3-enoate (0.3 g) and the mixture refluxed for 3 hours, cooled to room temperature, diluted with water (10 ml) and extracted with ether. The aqueous phase is acidified with 2N aqueous hydrochloric acid extracted with ether (×3), dried and the solvent evaporated under reduced pressure. Yield 0.25 g nD 1.4898.

Provenance & Evidence