HCID 54516331, compound → HCID 23353888, compound

HRID 235197Notes

Reaction equation

HRID 235197 reaction equation
[C:1]([C:11]1[CH:16]=[CH:15][C:14]([CH2:17][CH2:18][CH2:19][C:20]([O:22][CH3:23])=[O:21])=[CH:13][CH:12]=1)(=[O:10])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1>CO.[Pd]>[C:4]1([CH2:3][CH2:2][C:1]([C:11]2[CH:12]=[CH:13][C:14]([CH2:17][CH2:18][CH2:19][C:20]([O:22][CH3:23])=[O:21])=[CH:15][CH:16]=2)=[O:10])[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

4

Reactant 1

HCID 54516331HCID 54516331, compound

Product 1

HCID 23353888HCID 23353888, compoundYield 98.8%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

To a solution of 3.89 g of methyl 4-(4-cinnamoylphenyl)butyrate in 50 ml of methanol, 0.25 g of 10% palladium on carbon was added, and hydrogenation was carried out at an ordinary temperature and under ordinary pressure for 5 hours. The catalyst was filtered off and the filtrate was concentrated under reduced pressure to give 3.87 g of pale brown oil.

Workup

  1. filtrationThe catalyst was filtered off
  2. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-f810004691454dadb127cc60c74ba10a
Source dataset
uspto-grants-1997_01
Patent number
US05597848

Reaction notes

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