Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2352129Generated: October 30, 2026

5-Bromopyrimidine → HCID 19843738, compound

https://huagongshe.com/reaction/2352129

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-BromopyrimidineHCID 78344—
ReactantCyclopropanecarboxaldehydeHCID 123114—
ReactantButyllithiumHCID 178418339—
ProductHCID 19843738HCID 19843738—

Reaction Steps

Using the general method of Example 1, cyclopropanecarboxaldehyde (19 g, 0.27 mol) was reacted with 5-bromopyrimidine (43.2 g, 0.27 mol) and n-butyl lithium (108.6 ml of 2.5M, 0.27 mol) to give the product as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04875922
Source datasetuspto-grants-1989_10
ORD IDord-64ef6b42574b4263bdea3e29d721fd37
Source noteuspto-grants-1989_10