1-(2-Pyridyl)piperazine → HCID 86743469, compound

Participants

Reaction Steps

A solution of 465 mg. (0.004 mole) of maleic acid in 2 ml. of methanol was added to 327 mg. (0.002 mole) of 1-(2-pyridyl)-piperazine [K. L. Howard, H. W. Stewart, E. A. Conroy, ad J. J. Dentor, J. Org. Chem., 18, 1484 (1953)] in 1 ml. of methanol. The white solids which separated were recrystallized from methanol to yield 1-(2-pyridyl)-piperazine dimaleate, m.p. 140°-141° C.

Provenance & Evidence