反应详情

A mixture of 14.4 g of 3-dimethylamino-1-(3-pyridinyl)-2-propen-1-one and 16.1 g of 4-methoxyphenyl guanidine carbonate in 200 ml of isopropanol was heated at reflux for 20 hours. The reaction mixture was cooled, the crude product was collected by filtration and washed with water. The material was recrystallized from isopropanol to give the desired product as light yellow crystals, mp 121°-122° C.

1. temperaturewas heated
2. temperatureat reflux for 20 hours
3. temperatureThe reaction mixture was cooled
4. filtrationthe crude product was collected by filtration
5. washwashed with water
6. customThe material was recrystallized from isopropanol