Hydrochloric Acid → HCID 14347195, compound

HRID 2352181Notes

Reaction equation

HRID 2352181 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[CH:12]=[CH:11][N:10]=[C:9]([NH:13][C:14]2[CH:19]=[CH:18][C:17]([NH:20]C(=O)C)=[CH:16][CH:15]=2)[N:8]=1.[ClH:24]>O>[ClH:24].[ClH:24].[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[CH:12]=[CH:11][N:10]=[C:9]([NH:13][C:14]2[CH:19]=[CH:18][C:17]([NH2:20])=[CH:16][CH:15]=2)[N:8]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 14347153HCID 14347153, compound

Product 1

HCID 14347195HCID 14347195, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A 12.86 g portion of N-[4-[[4-(2-pyridinyl)-2-pyrimidinyl]amino]phenyl]acetamide in a mixture of 40 ml of water and 40 ml of concentrated hydrochloric acid was refluxed for 30 minutes and then cooled. The solid was collected and dried, giving 10.84 g of the desired product, mp 285°-288° C.

Workup

  1. temperaturewas refluxed for 30 minutes
  2. temperaturecooled
  3. customThe solid was collected
  4. customdried

Sources & evidence

ORD record
ord-8f30399ba10d48df8b8f868699a386b3
Source dataset
uspto-grants-1989_10
Patent number
US04876252

Reaction notes

Loading…