4-Aminophenol → HCID 13839894, compound
Reaction equation
[CH:1]1[C:6]([NH2:7])=[CH:5][CH:4]=[C:3]([OH:8])[CH:2]=1.Br[CH2:10][C:11]([N:13]1[CH2:18][CH2:17][N:16]([CH3:19])[CH2:15][CH2:14]1)=[O:12]>>[NH2:7][C:6]1[CH:5]=[CH:4][C:3]([O:8][CH2:10][C:11]([N:13]2[CH2:18][CH2:17][N:16]([CH3:19])[CH2:15][CH2:14]2)=[O:12])=[CH:2][CH:1]=1Participants
3
Procedure
Prepared from p-aminophenol and 1-(bromoacetyl)-4-methylpiperazine by the method of Example 333 to give a product of m.p. 71°-73° C.
Workup
- customto give a product of m.p. 71°-73° C.
Sources & evidence
- ORD record
- ord-9ea8d5207c3d4228809b206b2c7c317c
- Source dataset
- uspto-grants-1989_10
- Patent number
- US04876252
Reaction notes
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