Dicyclohexylcarbodiimide → 2-Dimethylaminopyridine

HRID 235229Notes

Reaction equation

HRID 235229 reaction equation
[CH3:1][C@H]1OC(=O)C2C(O)=CC(O)=C(Cl)C=2CC(=O)C=CC=C[C@H]2O[C@H]2C1.COCOCCCCCCCCCCCC(O)=O.[CH:44]1([N:50]=[C:51]=[N:52][CH:53]2[CH2:58][CH2:57][CH2:56]CC2)CCCCC1>O1CCCC1>[CH3:1][N:50]([C:51]1[CH:56]=[CH:57][CH:58]=[CH:53][N:52]=1)[CH3:44]

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 11268547CID 11268547HCID 19032998HCID 19032998, compound

Product 1

HCID 218852-Dimethylaminopyridine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following a procedure similar to that described in Example 12, but using 400 mg of radicicol, 716 mg of 12-(methoxymethoxy)dodecanoic acid, 7 ml of dry tetrahydrofuran, 567 mg of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 756 mg of the title compound were obtained.

Sources & evidence

ORD record
ord-c2bc4abce900461f9aec6f759bb74d5c
Source dataset
uspto-grants-1997_01
Patent number
US05597846

Reaction notes

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