Hexane → N-(2-Nitrophenyl)-N'-(3-bromo-4-ethoxyphenyl)-urea

HRID 235235Notes

Reaction equation

HRID 235235 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N:10]=[C:11]=[O:12])([O-:3])=[O:2].[Br:13][C:14]1[CH:15]=[C:16]([CH:18]=[CH:19][C:20]=1[O:21][CH2:22][CH3:23])[NH2:17].CCCCCC>C1(C)C=CC=CC=1>[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11]([NH:17][C:16]1[CH:18]=[CH:19][C:20]([O:21][CH2:22][CH3:23])=[C:14]([Br:13])[CH:15]=1)=[O:12])([O-:3])=[O:2]

Participants

5

Reactant 3

HCID 8058HexaneHCID 768342-Nitrophenyl isocyanateHCID 152708853-Bromo-4-ethoxyaniline

Product 1

HCID 21473031N-(2-Nitrophenyl)-N'-(3-bromo-4-ethoxyphenyl)-urea

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
20 °C

Procedure

To a solution of 2-Nitrophenyl isocyanate (3.34 g) in 100 mL of toluene was added 3-Bromo-4-ethoxyaniline (3.1 g). The mixture was stirred at 20° C. for 30 min. Hexane (300 mL) was added and the resulting solid was filtered and dried to yield N-(2-Nitrophenyl)-N'-(3-bromo-4-ethoxyphenyl)-urea as a light yellow solid.

Workup

  1. filtrationthe resulting solid was filtered
  2. customdried

Sources & evidence

ORD record
ord-c06e6e541095446bb7d71c417614983f
Source dataset
uspto-grants-1997_01
Patent number
US05597920

Reaction notes

Loading…