Chlorotrifluoroethylene → 2-Chloro-N,N-diethyl-1,1,2-trifluoroethan-1-amine

Participants

Reaction Steps

Chlorotrifluoroethylene (454 g; 3.91 mole) is bubbled into diethylamine (350 g; 4.8 mole) over about 6 hours while the temperature is maintained at 30°-45° C. by use of an ice bath. The mixture is stirred overnight at room temperature and then distilled in vacuo to give 415 g (2.2M) of N-(2-chloro-1,1,2-trifluoroethyl)-diethylamine.

Provenance & Evidence