4-Methylmorpholine → HCID 14819159, compound

Participants

Reaction Steps

Conducting a reaction and treatments in the same manner as in Step (3) of Example 1 except that N-(2-oxo-3-tetrahydrofuranyl)-L-alanine hydrochloride was used in a form neutralized with N-methylmorpholine in place of Isomer BCD of N-(2-oxo-5-octyl-3-tetrahydrofuranyl)-L-alanine, was obtained as a colorless syrupy substance N-(2-oxo-3-tetrahydrofuranyl)-L-alanyl-L-proline benzyl ester [in the formula (I), R1 =R2 =H, R3 =CH3, R4 and R5 =--(CH2)3 --, R6 =-CH2Ph (Compound 13)].

Provenance & Evidence