反应详情

温度

25 °C

A suspension of 3-morpholinomethyl-5-t-octylcatechol (564 g, 1.76 mole) and 193.4 g (1.76 mole) benzenethiol in 0.8 liter dimethylformamide was kept at 130° C. under a nitrogen atmosphere for 20 hours. The reaction mixture was cooled to 25° C. and diluted with 3,000 ml diethyl ether. The resulting solution was washed in turn with 3×1,000 ml water, 500 ml 10% hydrochloric acid, 500 ml water and 500 ml brine. The washed solution was dried over anhydrous magnesium sulfate and evaporated in vacuo to a yellow oil (548.9 g, 91% yield) of the title compound.

1. washThe resulting solution was washed in turn with 3×1,000 ml water, 500 ml 10% hydrochloric acid, 500 ml water and 500 ml brine
2. dry with materialThe washed solution was dried over anhydrous magnesium sulfate