Dimethylthiocarbamoyl chloride → HCID 20068261, compound

HRID 2352570Notes

Reaction equation

[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]([C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1)=[O:10])#[N:2].[CH3:18][N:19]([CH3:23])[C:20](Cl)=[S:21]>>[CH3:18][N:19]([CH3:23])[C:20](=[S:21])[O:17][C:14]1[CH:13]=[CH:12][C:11]([C:9](=[O:10])[C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[C:1]#[N:2])=[CH:16][CH:15]=1

Participants

Reactant 2

HCID 27871Dimethylthiocarbamoyl chloride

HCID 20068242HCID 20068242, compound

Product 1

HCID 20068261HCID 20068261, compoundYield 90.1%

Procedure

Following the procedure described in Preparation I and starting from 13.3 g (0.059 mol) of 2-cyanophenyl 4-hydroxyphenyl methanone and 8.5 g (0.068 mol) of dimethylthiocarbamoyl chloride, 16.5 g (yield: 89%) of O-4-(2-cyanobenzoyl)phenyl dimethylthiocarbamate melting at 138° C. are obtained.

Workup

customdescribed in Preparation I

Sources & evidence

ORD record: ord-d7f83e422d754e6da348069d8bddecaa
Source dataset: uspto-grants-1989_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04877808

Reaction notes

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