Dimethylthiocarbamoyl chloride → HCID 20068249, compound

HRID 2352571Notes

Reaction equation

[C:1]([C:3]1[CH:4]=[C:5]([C:9]([C:11]2[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=2)=[O:10])[CH:6]=[CH:7][CH:8]=1)#[N:2].[CH3:18][N:19]([CH3:23])[C:20](Cl)=[S:21]>>[CH3:18][N:19]([CH3:23])[C:20](=[S:21])[O:17][C:14]1[CH:13]=[CH:12][C:11]([C:9](=[O:10])[C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([C:1]#[N:2])[CH:4]=2)=[CH:16][CH:15]=1

Participants

Reactant 2

HCID 27871Dimethylthiocarbamoyl chloride

HCID 14622766HCID 14622766, compound

Product 1

HCID 20068249HCID 20068249, compoundYield 93.2%

Procedure

Following the procedure described in Preparation I and starting from 27 g (0.121 mol) of 3-cyanophenyl 4-hydroxyphenyl methanone and 17.2 g (0.138 mol) of dimethylthiocarbamoyl chloride, 35 g (yield: 88%) of O-4-(3-cyanobenzoyl)phenyl dimethylthiocarbamate melting at 160° C. are obtained.

Workup

customdescribed in Preparation I

Sources & evidence

ORD record: ord-9d67755828994aa7b7e9fdfe1ea92125
Source dataset: uspto-grants-1989_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04877808

Reaction notes

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