Phenyl isocyanate → Phenylurea

HRID 2353029Notes

Reaction equation

HRID 2353029 reaction equation
C1(N=C=O)C=CC=CC=1.CC1(C)OC2C(N3C=NC4C3=NC=NC=4[NH:40][C:41]([NH:43][C:44]3[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=3)=[O:42])OC(C(NC3C=C(C=CC=3)C(O)=O)=O)C2O1>>[C:44]1([NH:43][C:41]([NH2:40])=[O:42])[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1

Participants

3

Reactant 2

HCID 7672Phenyl isocyanateHCID 11203767HCID 11203767, compound

Product 1

HCID 6145Phenylurea

Procedure

Phenyl isocyanate was coupled with the amide product using a method similar to those described above, affording the intermediate phenylurea compound. MW calculated for C30H29N7O7 (MH+) 600, found 600 by LCMS.

Sources & evidence

ORD record
ord-b840fbac72514ffd9eccf3958e52544a
Source dataset
uspto-grants-2010_07
Patent number
US07749980B2

Reaction notes

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