Triethylamine → HCID 1122381, compound

HRID 2353120Notes

Reaction equation

HRID 2353120 reaction equation
[CH2:1]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:14][O:15][CH2:16][C:17](Cl)=[O:18].C(N(CC)CC)C>C(Cl)Cl>[CH2:1]([N:8]1[CH2:13][CH2:12][N:11]([C:17](=[O:18])[CH2:16][O:15][CH3:14])[CH2:10][CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 759941-BenzylpiperazineHCID 96623Methoxyacetyl chloride

Product 1

HCID 1122381HCID 1122381, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Amine preparation: a mixture of benzylpiperazine, methoxyacetyl chloride and triethylamine was stirred in DCM for 2 h to yield 1-(4-benzyl-piperazin-1-yl)-2-methoxy-ethanone following standard work up.

Sources & evidence

ORD record
ord-b98abacf63974131a435ed0b9cefd7a4
Source dataset
uspto-grants-2010_07
Patent number
US07750002B2

Reaction notes

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