Benzene, 1-iodo-4-(trifluoromethyl)- → HCID 68426458, compound

Participants

Reaction Steps

The title compound (120 mg, 25%) was prepared from 4-(4-benzyl-piperazin-1-yl)-phenol (268 mg, 1 mmol) and 1-iodo-4-trifluoromethyl-benzene (270 mg, 1 mmol) by the procedure described in step 2 of Example 17: MS (ESI) m/z 413 (M+H): 1H NMR (400 MHz, CDCl3) δ 2.63 (br, 4H), 3 18 (br, 4H), 3.58 (s, 2H), 6.92-6.98 (m, 6H), 7.32-7.35 (m, 5H), 7.52 (d, J=7.2 Hz, 2H).

Provenance & Evidence