Methyl triflate → HCID 73446474, compound

HRID 2353374Notes

Reaction equation

HRID 2353374 reaction equation
[CH2:1]([O:8][N:9]=[C:10]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:23][C:24]([F:31])([F:30])[S:25]([O:28]C)(=[O:27])=[O:26]>C(OCC)C>[F:23][C:24]([F:31])([F:30])[S:25]([O-:28])(=[O:27])=[O:26].[CH2:1]([O:8][N:9]=[C:10]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][N+:12]=1[CH3:24])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 9526Methyl triflateHCID 72741676HCID 72741676, compound

Product 1

HCID 73446474HCID 73446474, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a suspension of 35 g (120 mmol) of phenyl(2-pyridyl)methanone O-benzyl oxime in 200 ml of diethyl ether are added dropwise, at 0° C., 17.4 ml (120 mmol) of methyl trifluoromethanesulfonate and the mixture is stirred at room temperature for 3 hours. The precipitate formed is collected by filtration and dried under reduced pressure.

Workup

  1. additionare added dropwise, at 0° C.
  2. customThe precipitate formed
  3. filtrationis collected by filtration
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-af74891ce8404d3b949e33c86fe82204
Source dataset
uspto-grants-2010_07
Patent number
US07750025B2

Reaction notes

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