HRID23534

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(C(C)(C)C)cc1NC(=O)Nc1ccc(Oc2ccnc(C#N)n2)c2ccccc12

HCID9912417

未命名化合物

HCID10214710

未命名化合物

HCID22573847

未命名化合物

PRODUCTS

生成物

结构：COc1c(NC(=O)Nc2ccc(OC3CCOCC3)c3ccccc23)cc(C(C)(C)C)cc1NS(C)(=O)=O

HCID22573829

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from the above amine and N-(3-amino-5-tert-butyl-2-methoxyphenyl)methanesulfonamide by the procedure described for 1-(5-tert-butyl-2-methoxy-phenyl)-3-[4-(2-cyano-pyrimidin-4-yloxy)-naphthalen-1-yl] -urea (Example 1).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7a761836c6634eaf9c97d8920f70b95a
来源数据集: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06852717B2
来源说明: uspto-grants-2005_02

反应 SMILES

[O:1]1[CH2:6][CH2:5][CH:4]([O:7][C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11]([NH2:18])=[CH:10][CH:9]=2)[CH2:3][CH2:2]1.[NH2:19][C:20]1[C:21]([O:35][CH3:36])=[C:22]([NH:30][S:31]([CH3:34])(=[O:33])=[O:32])[CH:23]=[C:24]([C:26]([CH3:29])([CH3:28])[CH3:27])[CH:25]=1.C(C1C=CC(OC)=C(N[C:48](NC2C3C(=CC=CC=3)C(OC3C=CN=C(C#N)N=3)=CC=2)=[O:49])C=1)(C)(C)C>>[C:26]([C:24]1[CH:25]=[C:20]([NH:19][C:48]([NH:18][C:11]2[C:12]3[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=3)[C:8]([O:7][CH:4]3[CH2:5][CH2:6][O:1][CH2:2][CH2:3]3)=[CH:9][CH:10]=2)=[O:49])[C:21]([O:35][CH3:36])=[C:22]([NH:30][S:31]([CH3:34])(=[O:33])=[O:32])[CH:23]=1)([CH3:28])([CH3:29])[CH3:27]