HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(5-Tert-butyl-2-methoxy-phenyl)-3-[4-(2-cyano-pyrimidin-4-yloxy)-naphthalen-1-yl]-urea → n-(5-Tert-butyl-2-methoxy-3-{3-[4-(tetrahydro-pyran-4-yloxy)-naphthalen-1-yl]-ureido}-phenyl)-methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(5-Tert-butyl-2-methoxy-phenyl)-3-[4-(2-cyano-pyrimidin-4-yloxy)-naphthalen-1-yl]-urea | HCID 9912417 | — |
| Reactant | N-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamide | HCID 10214710 | — |
| Reactant | 4-(Tetrahydro-pyran-4-yloxy)-naphthalen-1-ylamine | HCID 22573847 | — |
| Product | n-(5-Tert-butyl-2-methoxy-3-{3-[4-(tetrahydro-pyran-4-yloxy)-naphthalen-1-yl]-ureido}-phenyl)-methanesulfonamide | HCID 22573829 | — |
Reaction Steps
The title compound was prepared from the above amine and N-(3-amino-5-tert-butyl-2-methoxyphenyl)methanesulfonamide by the procedure described for 1-(5-tert-butyl-2-methoxy-phenyl)-3-[4-(2-cyano-pyrimidin-4-yloxy)-naphthalen-1-yl] -urea (Example 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06852717B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-7a761836c6634eaf9c97d8920f70b95a |
| Source note | uspto-grants-2005_02 |