HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetamidine → HCID 86635440, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetamidine | HCID 2776882 | — |
| Reactant | (3R,4S)-rel-1-Boc--3,4-diaMinopyrrolidine | HCID 20677776 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86635440 | HCID 86635440 | — |
Reaction Steps
To the product from Step C (250 mg) in ethanol (5 mL) was added 2,2,2-trifluoroethanimidamide (180 mg) and the reaction mixture heated to reflux. After 2 h, the mixture was cooled to ambient temperature and the solvent evaporated in vacuo and used without further purification. LC/MS 224.2 (14+1-56).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07750034B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-e9408909e4314dc39c691e1b34b6aad8 |
| Source note | uspto-grants-2010_07 |