HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → (1-methyl-1H-imidazol-2-yl)methyl Methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | (1-methyl-1H-imidazol-2-yl)methanol | HCID 573612 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (1-methyl-1H-imidazol-2-yl)methyl Methanesulfonate | HCID 44627230 | — |
Reaction Steps
A solution of (1-methyl-1H-imidazol-2-yl)-methanol (Bionet Research, 66 mg, 0.59 mmol), triethylamine (0.25 mL, 0.89 mmol), and methanesulfonyl chloride (69 μL, 0.89 mmol) in 5 mL THF were processed as described in Example 1C to give the crude material which was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07750039B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-c1f77063eb134b749dec1fb9dce41dc6 |
| Source note | uspto-grants-2010_07 |