1-Bromo-2-propanol → HCID 68452904, compound

HRID 2353605Notes

Reaction equation

HRID 2353605 reaction equation
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][C:4]=1[O:10][CH3:11].Br[CH2:13][CH:14]([OH:16])[CH3:15]>>[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][CH2:13][CH:14]([OH:16])[CH3:15])=[CH:5][C:4]=1[O:10][CH3:11]

Participants

3

Reactant 2

HCID 297401-Bromo-2-propanolHCID 534043344-(Aminomethyl)-3-methoxyphenol

Product 1

HCID 68452904HCID 68452904, compound

Procedure

(rac)-1-(4-Aminomethyl-3-methoxy-phenoxy)-propan-2-ol is prepared starting from 4-aminomethyl-3-methoxy-phenol and (rac)-1-bromo-propan-2-ol in analogy to the procedures given in Example 18, steps a to c. LC-MS: tR=0.66 min, [M+1]+=212.13.

Sources & evidence

ORD record
ord-1aae84b69b6a47cf89f4bbdf2bedf062
Source dataset
uspto-grants-2010_07
Patent number
US07750040B2

Reaction notes

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