Hydrochloric Acid → HCID 86093247, compound

Participants

Reaction Steps

The above [4-(2-fluoro-ethoxy)-2-methoxy-benzyl]-carbamic acid tert-butyl ester (9.9 mg, 0.33 mmol) is treated with 37% aq. HCl (0.1 mL) and acetic acid (1 mL) for 1.5 h at rt. The solvents are removed by lyophilisation to give 4-(2-fluoro-ethoxy)-2-methoxy-benzylamine hydrochloride (7.8 mg) as a beige resin. LC-MS: tR=0.73 min, [M+1]+=200.04.

Provenance & Evidence