2-(Methylamino)ethanol → HCID 68707716, compound

Participants

Reaction Conditions

Reaction Steps

A solution of phenyl N-[4-[4-(methylsulfonylmethyl)-6-morpholin-4-yl-pyrimidin-2-yl]phenyl]carbamate (94 mg, 2 mmol) and triethylamine (0.09 mL, 9.2 mmol) in NMP (1 mL) was added to 2-methylaminoethanol (10 mmol). The mixture was heated at 70° C. for 2 hours and the reaction purified by prep HPLC, to give the desired compound.

Provenance & Evidence