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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2353766Generated: November 1, 2026

5-Aminosalicylic Acid → HCID 9879735, compound

https://huagongshe.com/reaction/2353766

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Aminosalicylic AcidHCID 4075—
Reactantp-Trifluoromethylbenzyl chlorideHCID 123096—
ProductHCID 9879735HCID 987973550.3%

Reaction Steps

By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-(trifluoromethyl)benzyl chloride (760 mg, 3.92 mmole), 510 mg (50% yield) of 5-(4-(trifluoromethyl)benzyl)aminosalicylic acid was obtained as a white solid.: mp>188° C. (decompose).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07750045B2
Source datasetuspto-grants-2010_07
ORD IDord-47af4a158645437d91c147791c31f435
Source noteuspto-grants-2010_07