HCID 68688967, compound → HCID 58816579, compound

Participants

Reaction Steps

A mixture of 4-(benzyl-methyl-carbamoyl)-4-phenyl-piperidine-1-carboxylic acid benzyl ester (4.4 g, 10 mmol) and Pd—C (10%, 400 mg) in MeOH (200 mL) is hydrogenated at r.t. and atmospheric pressure for 3 h. The mixture is filtered and evaporated. The residue is purified by reversed phase MPLC to provide the title compound.

Provenance & Evidence