HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68692193, compound → HCID 11271100, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68692193 | HCID 68692193 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 11271100 | HCID 11271100 | — |
Reaction Steps
A suspension of 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-[2-((E)-styryl)-pyridin-4-yl]-urea (Example 19., 47.0 mg, 0.1 mmol) and Pd—C (10%, 10 mg) in MeOH (10 mL) is stirred under hydrogen atmosphere for 15 h. The catalyst is filtered off and the reaction mixture evaporated to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07750161B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-63db95ebecc9449199d9432c24034ada |
| Source note | uspto-grants-2010_07 |