HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11410496, compound → HCID 11248845, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11410496 | HCID 11410496 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 11248845 | HCID 11248845 | — |
Reaction Steps
A suspension of 5-bromo-N-(1-{2-[3-(2,6-dimethyl-pyridin-4-yl)-ureido]-ethyl}-piperidin-4-yl)-N-ethyl-2-methoxy-benzenesulfonamide (Example 99, 30 mg, 0.05 mmol) and Pd—C (10%, 20 mg) in MeOH (10 mL) is stirred under hydrogen atmosphere for 15 h. The catalyst is filtered off and the reaction mixture evaporated to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07750161B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-4ab2423d426042eaa2d8ba5b132cc760 |
| Source note | uspto-grants-2010_07 |