Hydrochloric Acid → HCID 66919068, compound

Participants

Reaction Steps

Using an analogous procedure to that described in Example 45, 4N HCl in dioxane was reacted with N-cyclopropyl-3-[6-{[2-(dimethylamino)ethyl]thio}-4-oxoquinazolin-3 (4H)-yl]4-methylbenzamide to gave the title compound; NMR Spectrum: (DMSOd6) 0.58 (m, 2H), 0.70 (m, 2H), 2.15 (s, 3H), 2.70 (s, 6H), 2.85 (m, 1H), 3.14 (t, 2H), 3.45 (m, 2H), 7.53 (d, 1H), 7.78 (d, 1H), 7.85 (s, 1H), 7-91 (d, 1H), 7.95 (d, 1H), 8.12 (s, 1H), 8.31 (s, 1H), 8.50 (d, 1H), 10.65 (br s, 1H)

Provenance & Evidence