HuagongsheHuagongshe Chemistry Print Report · For research reference only
12-Methyl-5-(4-methoxybenzyl)-3,4,5,12-tetraaza-tricyclo[6.3.1.02,6]dodeca-2(6),3-diene → HCID 178479866, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 12-Methyl-5-(4-methoxybenzyl)-3,4,5,12-tetraaza-tricyclo[6.3.1.02,6]dodeca-2(6),3-diene | HCID 59679498 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 178479866 | HCID 178479866 | 65% |
Reaction Steps
12-Methyl-5-(4-methoxybenzyl)-3,4,5,12-tetraaza-tricyclo[6.3.1.02,6]dodeca-2(6),3-diene (0.5 g, 1.7 mmol) in trifluoroacetic acid (TFA) (6 mL) was heated at 65° C. overnight. The solvent was removed and the residue was purified by prep HPLC to afford the product (200 mg, 1.1 mmol, 65% yield) as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07754712B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-cec563aa954a4038a0d82f1b0dc5bede |
| Source note | uspto-grants-2010_07 |