Isopropanol → HCID 23093005, compound

HRID 2355020Notes

Reaction equation

HRID 2355020 reaction equation
C[O:2][C:3](=O)[C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[C:6](OCOC)[CH:5]=1.Br[C:17]1[CH:18]=[CH:19][C:20]([S:23]([CH3:26])(=[O:25])=[O:24])=[N:21][CH:22]=1.[NH2:27][C:28]1[CH:32]=[CH:31][N:30]([CH3:33])[N:29]=1.[OH:34][CH:35]([CH3:37])[CH3:36]>>[CH:35]([O:34][C:6]1[CH:7]=[C:8]([O:10][C:17]2[CH:22]=[N:21][C:20]([S:23]([CH3:26])(=[O:25])=[O:24])=[CH:19][CH:18]=2)[CH:9]=[C:4]([CH:5]=1)[C:3]([NH:27][C:28]1[CH:32]=[CH:31][N:30]([CH3:33])[N:29]=1)=[O:2])([CH3:37])[CH3:36]

Participants

5

Reactant 4

HCID 3776IsopropanolHCID 1372541-Methyl-3-aminopyrazoleHCID 134334245-Bromo-2-methanesulfonylpyridineHCID 23136427Methyl 3-hydroxy-5-(methoxymethoxy)benzoate

Product 1

HCID 23093005HCID 23093005, compound

Procedure

The compound of Production Example 130 was obtained as a white amorphous substance using 5-hydroxy-3-methoxymethoxybenzoic acid methyl ester, 5-bromo-2-methanesulfonylpyridine, 2-hydroxypropane and 3-amino-1-methyl-1H-pyrazole, by the same method as in Production Example 117, a corresponding method, or a combination thereof with an ordinary method.

Workup

  1. customThe compound of Production Example 130 was obtained as a white amorphous substance

Sources & evidence

ORD record
ord-9ef60a58d3ef499da60f1bca264be46f
Source dataset
uspto-grants-2010_07
Patent number
US07754743B2

Reaction notes

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