HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Diethoxy-4-fluoro-benzaldehyde → HCID 67400590, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Diethoxy-4-fluoro-benzaldehyde | HCID 59128273 | — |
| Reactant | HCID 67398466 | HCID 67398466 | — |
| Reactant | HCID 67401550 | HCID 67401550 | — |
| Product | HCID 67400590 | HCID 67400590 | — |
Reaction Steps
The title compound was prepared in analogy to the synthesis of 2-[1-(3-ethoxy-4-methyl-benzyl)-piperidin-4-ylamino]-isonicotinonitrile (example 189) from 2-(piperidin-4-ylamino)-isonicotinonitrile dihydrochloride (intermediate B15) and 3,5-diethoxy-4-fluoro-benzaldehyde (intermediate E5) in a yield of 4.3 mg (6%). MS (ISP): 399.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07754744B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-ca6451186442413fb987efc51704ce04 |
| Source note | uspto-grants-2010_07 |