HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 86645636, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 67543074 | HCID 67543074 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 86645636 | HCID 86645636 | 77% |
Reaction Steps
1-(4-Dimethylamino-phenyl)-2-{2-[3-(3-piperidin-1-yl-propoxy)-phenyl]-pyrrolidin-1-yl}-ethanone. Prepared as described in Example 8, Step 1, on a 2.70 mmol scale, to give 0.93 g (77%) of the desired product as a viscous oil after chromatography (NH3 in MeOH/CH2Cl2). MS: exact mass calcd for C28H39F3N3O2, 449.3; m/z found, 450.5 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07754882B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-fda658fb01d1413f9d7450c81a0fafe1 |
| Source note | uspto-grants-2010_07 |