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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2355829Generated: October 30, 2026

Ammonia → HCID 86645636, compound

https://huagongshe.com/reaction/2355829

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 67543074HCID 67543074—
SolventDichloromethane methanolHCID 21226129—
ProductHCID 86645636HCID 8664563677%

Reaction Steps

1-(4-Dimethylamino-phenyl)-2-{2-[3-(3-piperidin-1-yl-propoxy)-phenyl]-pyrrolidin-1-yl}-ethanone. Prepared as described in Example 8, Step 1, on a 2.70 mmol scale, to give 0.93 g (77%) of the desired product as a viscous oil after chromatography (NH3 in MeOH/CH2Cl2). MS: exact mass calcd for C28H39F3N3O2, 449.3; m/z found, 450.5 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07754882B2
Source datasetuspto-grants-2010_07
ORD IDord-fda658fb01d1413f9d7450c81a0fafe1
Source noteuspto-grants-2010_07