HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-(4-hydroxy-4-phenylpiperidin-1-yl)benzoate → HCID 22730374, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-(4-hydroxy-4-phenylpiperidin-1-yl)benzoate | HCID 22730002 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 22730374 | HCID 22730374 | — |
Reaction Steps
A solution of Example 493A (0.32 g, 0.91 mmol) in TFA (2 mL) at room temperature was stirred for 1 hour, and concentrated. The concentrate was azeotropically distilled with toluene three times and dried to provide the desired product. MS (ESI(+)) m/e 298 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07754886B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-eedf2c4dce524f538bffda8eb99cadcb |
| Source note | uspto-grants-2010_07 |