反应详情

To 25 mL of dehydrated ethanol, 2.5 g (4.7 mmol) of 4-benzyloxy-2-chloro-benzoic acid 4-(4-pentyl-phenoxycarbonyl)-phenyl ester, 20 mL of cyclohexene, and 0.13 g of palladium hydroxide/carbon were added. Then, the mixture was refluxed for 12 hours under argon. The resulting reaction mixture was filtered, and the filtered liquid was concentrated. The residue was recrystallized from hexane/ethyl acetate. As a result, 1.65 g of a white solid was obtained.

1. temperatureThen, the mixture was refluxed for 12 hours under argon
2. customThe resulting reaction mixture
3. filtrationwas filtered
4. concentrationthe filtered liquid was concentrated
5. customThe residue was recrystallized from hexane/ethyl acetate