HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-Chloro-1-{[(4-chloro-2-fluorophenyl)methyl]oxy}-2-iodobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Chloro-2-iodophenol | HCID 620234 | — |
| Reactant | 4-Chloro-2-fluorobenzyl bromide | HCID 2736551 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4-Chloro-1-{[(4-chloro-2-fluorophenyl)methyl]oxy}-2-iodobenzene | HCID 24753687 | — |
Reaction Steps
As for Reaction 1, using 84.87 g 4-chloro-2-iodophenol, 76 g 4-chloro-2-fluorobenzyl bromide and 92 g potassium carbonate in 900 ml acetone. Yield 129.36 g. Identical by TLC with product of Reaction 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07759369B2 |
| Source dataset | uspto-grants-2010_07 |
| ORD ID | ord-d74ff76d7d5c4a4dae6850e515f5d686 |
| Source note | uspto-grants-2010_07 |